Product Name: Mangosteen 500mg
Pure Mangosteen is a superfood supplement for your body comes from South Pacific and Asia. It has high health support qualitites and nutritional values. It is one of the potent antioxidant which may support healthy immune system and promotes healthy skin, hair and nails.
Manogosteen is well known as Queen of Tropical Fruits because of its great taste and many health support value. It is one of the high quality daily food supplement provides all the nutrition.
Mangosteen is harvested mainly in the tropical forests of East Asia. Its white, soft and juicy flesh is sweet and aromatic. It contains a potent concentration of Xanthones, one of the most powerful anti-oxidants ever discovered.
Mangosteen has remained relatively unknown in North America and Europe until recently. In Asia the health benefits of Mangosteen have been revered for centuries.
Pure Mangosteen 500mg
Hydroxypropyl Methylcellulose (HPMC) Capsule Shell, Magnesium Stearate, Silicone Dioxide.
Benefits / Uses:
• Powerful antioxidant which helps protect against free radicals.
• Contains Anti-Inflammatory properties.
• Works as Anti Carcinogenic agent.
• Makes the Bowel healthier act as fiber.
• Great source of vitamin C act as antioxidant.
• Maintain Blood Pressure
• May help to support a healthy immune system.
• May help support healthy skin, hair and nails.
Direction to use:
Take 2-4 Capsules Daily with a glass of water. Store in a cool, dry place and keep out of the reach of children.
Any supplement must not be used as substitute for a varied and balance diet and a healthy lifestyle.
If pregnant, breastfeeding OR taking any other medication please consult your doctor or healthcare professional before use.
Please discontinue this product on immediate basis if any side effect occurs and consult your doctor.
Do not exceed the stated dose unless under medical supervision
Not intended to use by person under the age of 18. Keep out of sight reach of children
Store in a cool, dry place.
Always read the label before use.
Not suitable for anyone wishing to remove rice or corn from their diet. This product is manufactured in a facility that also handles allergy based materials such as nuts, seeds, milk, egg, cereals, soya, mustard, celery, fish, crustaceans and sulphites.
Dairy, Gluten, GMO(Genetically Modified Food) , Lactose, Maize, Soya,Starch, Wheat,Yeast.
The xanthone, gamma-mangostin, potently inhibited prostaglandin E 2 (PGE 2 ) release and competitively inhibited the activities of both COX-1 and COX-2 enzymes in C6 rat glioma cells. These enzymes are major mediators in regulating inflammation. 1 Gamma-mangostin also inhibited IkappaB kinase activity associated with expression of the COX-2 enzyme. 2 In addition, alpha-mangosteen has potent inhibitory activity against prostaglandin PGE 2 release. 3 Alpha- and gamma-mangostins both inhibited nitrite production of lipopolysaccharide activated macrophage cells. 4
Several xanthones isolated from the fruit hulls of mangosteen have antifungal activity against 3 phytopathogenic fungi, Fusarium oxysporum vasinfectum , Alternaria tenuis , and Dreschlera oryzae . 5 Mangosteen also has activity against the dermatophytes Trichophyton mentagrophytes , Microsporum gypseum , and Epidermophyton floccosum
The xanthones from mangosteen may be useful in treating Helicobacter pylori digestive tract disorders such as peptic ulcer, gastritis, and gastric cancer. 6
A study in rats documents the efficacy of alpha-mangostin against cardiotoxicity and beta-adrenergic catecholamine-induced myocardial toxicity and oxidative stress. 7 Mangosteen also inhibits oxidative changes in human LDL by acting as a free radical scavenger to protect LDL. 8 , 9
The phenolic compounds from the hull of mangosteen have strong antioxidant activity in 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assays. 10 One study documents neuroprotective activity of extracts of the fruit hull. 12 Similar studies document the antioxidant and ferric-reducing activity of mangosteen compared with various fruits. 13 , 14
1. Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol . 2002;63(1):73-79.
2. Nakatani K, Yamakuni T, Kondo N, et al. Gamma-mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Mol Pharmacol . 2004;66(3):667-674.
3. Chen LG, Yang LL, Wang CC. Anti-inflammatory activity of mangostins from Garcinia mangostana . Food Chem Toxicol . 2008;46(2):688-693.
4. Wang CC, Chen LG, Lin LH, Yang LL. Inducible nitric oxide synthase inhibitors of Chinese herbs IV: Garcinia mangostana . American Chemical Society . 2004;AN 2004:655096
5. Gopalakrishnan G, Banumathi B, Suresh G. Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives. J Nat Prod . 1997;60(5):519-524.
6. Hasegawa H, Sakai S, Aimi N, Takayama H, Koyano T. Helicobacter pylori inhibitors containing xanthones from Garcinia mangostana . Kokai Tokkyo Koho Jpn . 1996;AN 1996:707533.
7. Sampath PD, Vijayaragavan K. Ameliorative prospective of alpha-mangostin, a xanthone derivative from Garcinia mangostana against beta-adrenergic cathecolamine-induced myocardial toxicity and anomalous cardiac TNF-alpha and COX-2 expressions in rats. Exp Toxicol Pathol . 2008;60(4-5):357-364.
8. Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin L. Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Radic Res . 1995;23(2):175-184.
9. Li P. Garcinia mangostana pericarp extract, its extraction and medical application. Faming Zhuanli Shenqing Gongkai Shuomingshy . AN 2006:1003483.
10. Yu L, Zhao M, Yang B, Zhao Q, Jiang Y. Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities. Food Chem . 2007;104(1):176-181.
12. Weecharangsan W, Opanasopit P, Sukma M, Ngawhirunpat T, Sotanaphun U, Siripong P. Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen ( Garcinia mangostana Linn.). Med Princ Pract . 2006;15(4):281-287.
13. Okonogi S, Duangrat C, Anuchpreeda S, Tachakittirungrod S, Chowwanapoonpohn S. Comparison of antioxidant capacites and cytotoxicities of certain fruit peels. Food Chem . 2007;103(3):839-846.
14. Patthamakanokporn O, Puwastien P, Nitithamyong A, Sirichakwal PP. Changes of antioxidant activity and total phenolic compounds during storage of selected fruits. J Food Compost Anal . 2008;21(3):241-248.